Autism and Air Pollution: Any Connections in Between? | Duke Kunshan University
Autism and Air Pollution: Any Connections in Between?
duke global health
Dr. Yanbo Teng

Postdoctoral fellow of Environmental Health in Global Health Research Center, Duke Kunshan University

Feb 07th 2018 12:00 to 13:00
Room 1079, Academic Building
Tuesday, February 13, 2018 - 16:15

Summary of talk:     

Autism spectrum disorder (ASD) has undergone a transition from rare disease to epidemic in China since 21st century, creating serious social and economic burdens. Although recent genomics studies have uncovered the genetic etiology in 20-30% of ASD cases, the increase in new cases of ASD in US has intensified the debate of whether gene-environment interaction contributes to susceptibility of ASD. Almost all studies conducted so far use case-control experimental design, leaving the environmental exposure unmeasured. Thus, no conclusion for the causality has been reached due to the nature of a retrospective design. In view that urban air pollution levels in China have been steadily increase in the last decades and a trend of increase in ASD has been observed, we hypothesized that the maternal and early postnatal environmental exposure primarily air pollution has significant adverse impact on the neurodevelopment and contribute to the susceptibility of autism in Children. In this study, we established prospective cohorts with 40000 pregnant women and their offspring and optimized the experimental protocols to measure the environmental exposure and evaluate the neurodevelopmental outcome in 0-5 year-old children.

Brief Biography:

Teng Yanbo is a postdoctoral fellow under Jim Zhang’s supervision in Global Health Research Center in Duke Kunshan University. He received doctoral training at department of pharmacy, National University of Singapore and has expertise in pharmacology and toxicology. Before that, he worked as a regulatory chemist in Rotam Cropsciences. Now his research focuses on novel biomarker development and the complex interactions between human factors and environmental exposures in order to understand how risk factors affect human health at the individual and population levels.